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A bromide dominance condition may develop when bromide,
acquired through environmental, occupational, iatrogenic or dietary
exposure, causes bromide levels in the body to rise high enough to
inhibit iodine enzyme metabolism.
Effects of Bromide on the Organs
Iodine depletion weakens the thyroid and other organs. (2)(3)(4)(5)(6) In
individuals where the bromide-iodine ratio is less, bromide may not be
problematic.
Thyroid
Elevated bromide levels have been implicated in every thyroid disease,
from simple hypothyroidism to auto-immune diseases to thyroid cancer.
Malenchenko found bromide levels 50 times higher in thyroid cancer than
normal thyroid tissue. (7)
Rats fed even the minimal amount of bromine expected to be encountered
in the environment underwent goiter-like changes (8), an arguable case of
bromide dominance. In the FIRE project, exposing rats to the brominated
flame retardant compound, bromocyclodecane, showed consistent effects
on the thyroid hormone axis, including decreased T4. Thyroid gland cells
have increased size and larger nuclei, indicating increased synthetic
activity. (9)
With enhanced intake of bromide, fully one-third of the iodine content in
the thyroids of rats was replaced by bromide. (10)
Skin
Skin biopsied from a woman who had been on bromide-containing
sedatives for nearly four years found increased bromide in normal skin
and three times that in an affected skin lesion. (11)
An infant administered a syrup containing sodium bromide developed
vegetative lesions on the face and scalp. (12)
Technicians exposed to brominated compounds for prolonged periods
developed multiple cherry angiomas on the trunk and extremities. (12)
Mental
The psychiatry literature abounds with cases of elevated bromide levels
being implicated in mental conditions from depression to schizophrenia.
(14)(15)(16) As Guy Abraham, MD, asks, “How many people with
misdiagnosed bromism are currently treated with psychiatric drugs?”(17)
Bromide was used to suppress women’s sex drive in the 1950s.
Source: http://www.breastcancerchoices.org/bromidedominancetheory.html